Clinical Decision Support
Medical Device grade apps and models in
Gynecological Ultrasound
Decision support applications
Gynaia develops and delivers software tools that support accurate, standardized, and reproducible clinical decisions in gynecological ultrasound. Our applications are based on validated diagnostic models developed within the IOTA, IETA, and other study frameworks, and are designed for use in routine practice, research, and training.
All apps are accessible on smartphones and via the web, and designed for certified professionals working in gynecology, oncology, obstetrics, fertility, and early pregnancy care.
ADNEX App: Classifying Adnexal Masses with Confidence
The ADNEX app supports clinicians in estimating the risk that an adnexal mass is benign, borderline, or malignant - distinguishing between several subtypes of ovarian tumors.
Based on the internationally validated ADNEX model developed by the IOTA consortium, this tool now includes an updated version of the model (ADNEX2), improving diagnostic performance across a broader patient population, including conservatively managed cases.
About the ADNEX App
The ADNEX app provides a user-friendly interface for applying the IOTA ADNEX risk model in clinical practice. It helps clinicians assess the risk of various types of adnexal masses, supporting better diagnostic accuracy and treatment planning.
With the latest ADNEX2 model update, the app now offers improved performance and broader applicability, including cases that are being managed conservatively. The interface is designed for efficient data entry and clear result presentation.
- Built on data from over 5,000 patients across multiple international centers
- Validated in over 40 peer-reviewed studies
- Includes the most recent model version (ADNEX2)
- Compliant with current medical device regulations
- Available as a web app and smartphone app
- Access restricted to certified users to ensure correct use
- Paired with training and membership programme for continuous learning
Coming Soon: Endometrial and Early Pregnancy Decision Tools
In addition to the ADNEX app, Gynaia is developing clinical decision support tools for other key areas in obstetrics & gynecology ultrasound. These tools are being created in close collaboration with clinical experts and built within established regulatory frameworks.
Endometrial App (IETA Model)
This upcoming application will assist in evaluating endometrial abnormalities, including intracavity lesions and suspected endometrial cancer. It incorporates IETA terminology and scoring systems, with structured input fields and contextual guidance to support consistent reporting.
- Based on the IETA framework (International Endometrial Tumor Analysis)
- Designed for endometrial thickness assessment, vascularity scoring, and lesion characterization
- Integrates structured reporting elements and terminology
- Suitable for use in routine practice and clinical research
Early Pregnancy Decision Support
Gynaia's early pregnancy tool combines two validated models to support clinical decision-making in challenging early pregnancy scenarios:
M6/PUL Model:
Estimates the risk of ectopic pregnancy in women with a pregnancy of unknown location (PUL) using clinical data (age, pain, bleeding, history of ectopic pregnancy) and biochemical markers (β-hCG and progesterone). Helps triage patients into low- or high-risk categories and guides appropriate follow-up.
PUV Model:
Assesses the likelihood of viability in intrauterine pregnancies of uncertain viability (PUV) based on clinical features (age, bleeding, gestational age) and ultrasound findings (gestational sac size and yolk sac presence).
Validation studies have shown high discriminatory performance across large, prospective cohorts.
Certified Use and Integrated Learning
All Gynaia apps are part of a broader learning and certification ecosystem. Access is limited to trained professionals who complete the corresponding modules within our Learning Management System. This ensures safe, effective, and evidence-based use of each model in clinical practice.
Evidence-Based. Clinician-Centric. Globally Accessible.
Gynaia's platform is designed to support ultrasound practitioners at every level—from clinical decision-making to ongoing education and quality assurance. Each tool is grounded in published evidence and integrated with structured learning pathways to support continuous improvement.